ElectroMechanical Membrane - Enabled Transfer ( EMMET ) System

With the explosion of proteomics and protein engineering, modern medicine and life science has taken a strong foothold in bench-scale laboratories, both academic and industrial. A vital component of benchscale development of protein-based technologies is purification. Engineered proteins often undergo a stage of the purification process termed ultrafiltration separation. This involves the separation of the protein of interest from their non-proteinaceous solvent components such as salts (e.g. NaCl) and small molecule denaturants (e.g. DTT, imidazole, urea). This is most commonly accomplished by way of ultrafiltration membrane exchange against a concentration gradient of solutes.